Health officials have announced 10 further coronavirus-related deaths and 592 new cases.
Eight of the deaths happened this month, with one in February and one in January.
It takes the death-toll in Ireland to 4,509 and the national case total to 225,179.
This morning, there were 359 COVID-19 patients in Irish hospitals with 82 people in intensive care with their symptoms.
The Deputy Chief Medical Officer Dr Ronan Glynn noted that today marks the anniversary of the first coronavirus-related death in Ireland.
“More than 4,500 people have lost their lives with this disease,” he said. “We remember them and their families and friends, as well as the many people who remain seriously ill or who are dealing with long-term health issues because of COVID-19.
“We now have three vaccines and a fourth authorised by the European Medicines Agency today, which offers us a way out of this pandemic.
“We must continue to protect as many people as possible from the severe effects of COVID-19 and to give people a chance to become vaccinated over the next number of weeks and months.
“Your efforts to limit contacts and follow the public health advice is not in vain, it is to protect people and it directly saves lives.”
Of the cases announced this evening, 253 were in Dublin, with 52 in Kildare, 35 in Donegal, 33 in Meath, 28 in Galway and the rest spread across all other counties.
The 14-day incidence of the virus in Ireland now stands at 162.1 cases per 100,000 people.
Longford still has the highest rate in the country after rising to 440.4 cases per 100,000.
In all, five counties now have rates higher than 200.
As of Monday, 536,617 vaccine doses had been administered in Ireland.
Some 382,528 people had received their first dose while 154,089 people were fully vaccinated.