The Match of the Day in the Premier League is at the wrong end of the table.
Second from bottom West Ham Utd take on Cardiff City - the team two places and three points ahead of them at the Cardiff City Stadium.
It's a must not lose for either team but especially for the West Ham manager Sam Allardyce who faces the sack if he returns to London with nothing to show for his efforts.
For Cardiff boss Ole Gunnar Solskjaer it's his first outing in the League after a successful start to management in England in the FA Cup.
There's another significant shoot out at the relegation end with rockbottom Sunderland bringing fifth from bottom Fulham to the Stadium of Light.
At the top end Chelsea will go top if they go to Hull City and collect the three points in the early kick off at the KC Stadium.
Man U have lost their last three games in all competitions and look to stop the rot against a Swansea City side going for a second win in a week at Old Trafford.
Everton have surpassed all expectations already and can nip back into a Champions League spot at Goodison Park if they overcome Norwich City.
Spurs bring Crystal Palace to White Hart Lane and it's Southampton against West Brom at St Marys.
In the Scottish Premiership there are games at Hearts, Partick Thistle and St Johnstone.