Moore Street could be no more after traders said they were willing to cease trading at the historic market.
It's been operating in the city for 200 years.
A document signed by 17 traders has been sent to Dublin City Council, which says say they want to leave the market.
A recent Government report showed a lack of toilets, crime, and anti-social behaviour was leading to its decline.
In August, the Corporation Fruit Market closed in Smithfield, with the victorian building to get a makeover.
The Irish Times reports that council chiefs said traders at Moore Street have one-year leases similar to renting a property.
Independent TD Maureen O'Sullivan has said that the traders are looking to meet with the council to sort out the future of the market.