Gardaí are continuing to question five people following three separate drug seizures in counties Louth, Dublin and Wexford.
Over four million euro worth of heroin was located after an articulated truck was stopped and searched on the M1 near Drogheda on Thursday night.
Two men and a woman - aged in their 40s - were arrested.
In a separate operation - two men - aged 27 and 37 were arrested after more than two million euro worth of cocaine was seized at a house on the Stillorgan Road in Donnybrook, in Dublin on Thursday.
Elsewhere, half a million euro worth of drugs - including heroin and ecstasy - was seized by Customs officers at Rosslare Europort in Wexford yesterday morning. Two men were arrested.
Both men were charged last night when they appeared before a special sitting of Gorey District Court.