The big team had avoided each other in the 3rd and 4th round of the FA Cup, but there will be some major casualties in the 5th round.
The four biggest teams left in the competition have been drawn together, as Manchester City will be at home to Chelsea, and Arsenal will host Liverpool.
Manchester City v Chelsea
Sheffield United or Fulham v Nottingham Forest or Preston
Arsenal v Liverpool
Brighton v Hull
Cardiff v Wigan
Sheffield Wednesday v Charlton
Sunderland v Southampton
Everton v Swansea
Matches to be played on the weekend of February 15-16.
