The number of people in intensive care with COVID-19 has fallen below 100 for the first time in over eight weeks
99 patients are in ICUs in public hospitals which is less than half the number in late January.
It is also the lowest level since January 7th when 101 people with coronavirus were in intensive care.
There are currently 401 patients in hospital with the virus - the lowest this year.
It comes as nine additional deaths related to COVID-19 and 522 new confirmed cases were reported in Ireland yesterday.
The CEO of the HSE Paul Reid said the decrease in ICU figures was "a great sign", while the Deputy Chief Medical Officer Dr Ronan Glynn says all the key indicators are going in the right direction and "real progress" is being made.
Meanwhile, the HSE is on target to deliver the first doses of COVID-19 vaccines to 1,300 GP practices this week.
The health service says the remaining 65 will receive them next week, allowing them to start the rollout on the over-85s.
The HSE has also promised to improve the timing of confirmation notices to GPs in relation to order numbers and delivery dates, saying 48 hours is not enough.
It comes as the Taoiseach acknowledged it will be "very challenging" for the country to meet its vaccination target for the end of March.
Micheál Martin previously said the aim was for 1.25 million doses to be administered by that point.
So far, less than 461,000 have been given out, with the target for last week missed by over 18,000.