Hundreds of protesters are marching through Dublin city centre towards the Israeli embassy.
They gathered at the Spire on O'Connell Street and then made their way to the Dail.
The group is staging the demonstration in solidarity with those caught up in the conflict in Gaza.
Emergency services say more than 120 people have died during five days of Israeli airstrikes, in response to rocket attacks by Hamas militants.
Officials say the latest strike over a northern Gaza town hit an association for the disabled.
Martin O' Quigley is Chairman of The Ireland Palestine solidarity campaign.
He says many Irish people aren't aware of how serious the crisis in Gaza really is.