Tommy Bowe suffered a suspected fractured leg in his one minute cameo during Ireland's Six Nations loss to Wales.
Leinster's Fergus McFadden has been drafted into the squad in his stead and will train with the squad this week.
Scrum-half Conor Murray should be fit to face England at the Aviva Stadium on Saturday.
A shoulder injury forced the Munster man off during the 22-9 defeat in Cardiff. Team manager Paul Dean says he has recovered and will be available for selection:
“Conor Murray sustained a stringer injury in his left shoulder, he’s responded well to treatment and is available for selection.
“He’s fine today, unfortunately a stinger injury is a peculiar injury its kind of a numbness that happens on the pitch, you recover quite quickly.
“Iain Henderson had a bad one against France but he recovered very quickly and he was able to stay.
“Conor is such a good player and we gave him as much opportunity to recover from the stinger and as you all saw he didn't recover completely and we had to take him off.
Struggling with his passing and in clear discomfort Murray continued after the initial injury, having been eventually replace by Kieran Marmion it was put to Ireland team manager Paul Dean that perhaps allowing the one armed Murray to continue was a mistake:
“You have to give the player every opportunity to continue, Conor is such a good guy and such a valuable asset to us we needed to allow him to stay on as long to allow him to recover.
“He wasn't comfortable enough to continue so the best thing to do was take him off."
Johnny Sexton passed a HIA on the night and will train fully this week, Jared Payne played for Ulster in their win over Zebre last weekend. He'll rejoin the squad and is expected to train fully this week.