A report carried out by Sinn Féin Deputy Leader Mary Lou McDonald TD showed there were a total of 59,173 appointments rescheduled in 2016. This is an increase of nearly 24,000 since 2010.
The high amount of appointments being cancelled by the hospital has led to more then 1 out of 10 people not attending their second appointment.
The report on The Mater Hospital's current problems was launched earlier today and also offers possible solutions.
The document states that more money needs to be put into the city centre hospital to improve over crowding, long waiting lists, cancellations on appointments, agency spend and patient waiting times.
The party say there are not enough employees working at The Mater and due to the healthcare system in place, the sector is becoming less attractive to work in.
The number of people attending the emergency department has also increased with limited staff and beds this is becoming a difficult problem to tackle at the hospital.
The amount spent on agency staff totalled to €4,581,016 last year. The panel presenting the report said this money needs to be spent on improving the hospitals own staff instead of out letting from companies.
Mary McDonald said, "There are 40 people on trolleys today in The Matter so the situation continues".
"The kinds of pressures that The Matter Hospital is under, it reflects more broadly the pressures within the health service and it is the bases for which a very important discussion needs to now happen".
"Very often people have the idea that we actually can't sort out the health service, I know from talking to people in the community that a lot of people believe that it's not doable, well the fact is that it can be done".
Stephen McMahon from the Irish Patients Association talked about what he believes everyone should have in terms of healthcare;
"Respect and support for individual wants, preferences, values, needs and rights. This is irrespective of a persons social stand and class, religion, ethnic origin or whatever else, it is common to us all as human beings".
TD and Sinn Féin's spokesperson for health Louise O'Reilly also talked about her disappointment with the current situation at the hospital.
"We need to be aware that there is another way, there is alternative solutions, there is not only one way to run our health service".
"I want to this morning, thank the workers in The Matter... I want to thank the people who are at the business end of healthcare because those people are the ones who are really dealing with the failure".
"When you've been 22, 23, 24, 25, 26, multiple hours waiting with an elderly relative or waiting with a sick relative, there is no dignity".