Trucks have dumped the first delivery of waste off at the Poolbeg incinerator. It will start burning this weekend, and provide enough electricity for 80,000 homes by the end of next month.
Many residents remain opposed to the development, which was first proposed 20 years ago.
However, Dublin Chamber, the group which represents businesses in the capital, has welcomed the opening of the incinerator.
Mary Rose Burke believes the incinerator "will have a positive effect on the cost base for Irish business".
"Incineration is recognised globally as an effective method of waste management. Ireland's recycling rates have dramatically increased in recent years and the new incinerator will help ensure that Ireland meets the EU target to reduce landfill", she said.