Three people have been taken to hospital after a serious crash on the South Quays.
A large section of the route is still closed to traffic, after four vehicles were involved in the collision this afternoon.
Pictures appear to show a taxi, car and truck involved in the collision at Wellington Quay, close to Parliament Street.
Drivers can divert via D'Olier St and Dame St, but are being told to avoid the area altogether.
The College Green traffic ban has been lifted for now, and emergency services are at the scene.